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Cryo-TEM – Thermo Fisher Scientific Talos Arctica

Provide high-resolution 3D characterization of biological and biomaterial samples for detailed insights into the structure and function of complex biological system 

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Description

The Thermo Fisher Scientific Talos Arctica is a 200kV field emission Cryo-Transmission Electron Microscope (Cryo-TEM) managed in partnership with the Victor Chang Cardiac Research Institute.

This powerful, stable, and versatile system excels in delivering high-resolution 3D characterization of biological and biomaterial samples. It is particularly ideal for researchers in cell biology, structural biology, and nanotechnology. The Talos Arctica features advanced automation and high-throughput capabilities, including robotic sample handling and automated loading for up to 12 samples, enhancing data acquisition speed and efficiency. Additionally, it is sophisticated software suite supports a wide range of applications, from single-particle analysis to tomography, making it an inviable tool for researchers aiming to achieve detailed insights into the structure and function of complex biological systems.

Specifications

    • Electron Gun: X-FEG 
    • Resolution: <0.23nm 
    • Autoloader: automated loading of 12 grids 
    • Camera: 4k x 4k Falcon 3EC direct electron detector 

                             4k x 4k CETA CCD 

    • Phase Plate: Volta Phase Plate 
    • Tilting angle: -70o to +70o

Publishing Microscopy Data Acquired on the ThermoFisher Scientific Talos Arctica

      • Manufacturer: Thermo Fisher Scientific 
      • Model: Talos Artica
      • Type: x-FEG
      • Accelerating voltage: 200 kV
      • Detectors: Falcon 3EC direct electron detector or Ceta-M camera 

    Acknowledgement:

    “The authors acknowledge the use of the Cryo Electron Microscopy Facility through the Victor Chang Cardiac Research Institute Innovation Centre, funded by the NSW government, and the Electron Microscope Unit within the Mark Wainwright Analytical Centre (MWAC) at ¼ Sydney.”

    Credit EMU staff: Feel free to mention EMU staff who have assisted you with your work! If staff have been involved with your work beyond basic training and support (e.g., project design, complex data/image processing, independent imaging/analysis, manuscript preparation), it may be appropriate to discuss co-authorship with the relevant staff and your supervisor.

    Don’t forget to email the EMU lab manager with a copy of your publication to claim 2 hours of free microscopy time.

Applications

  • Life Science 
  • Medical science 
  • Pharmaceutical industry 
  • dzٱ
  • Solar and battery materials 
  • Earth Science 
  • Materials Science

Capabilities

  • Low Dose Imaging 
  • Automatic cryo
  • EM acquisition for Single Particle Analysis 
  • Batch cryo-electron Tomography (cryo-ET) 
  • Microcrystal Electron Diffraction

Funding partners

Instrument location

Electron Microscope Unit

22,𳾱Գ
Hilmer Building (E10)
¼ Sydney, NSW 2052

Access – To discuss training or how your project could benefit from using this microscope, please contact the EMU using the or  email EMUAdmin@unsw.edu.au

Dr Juanfang Ruan

Senior Research Associate

Dr Daniel Luque

Associate Director Electron Microscope Unit

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