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Dr Saeed Shanehsazzadeh

Dr Saeed Shanehsazzadeh

Postdoctoral Fellow
Research & Enterprise
Bio Resources Imaging Lab

Saeed Shanehsazzadeh, PhD, received his Ph.D. in medical physics from the Tehran University of Medical Sciences in 2013. In his post-doctoral career, he further specialized in nanoparticle tracer development and characterization and was able to make significant contributions in the field of antibody labelled radioisotopes. From more than 10 years of research work in international molecular imaging, nanomedicine and multidisciplinary medical sciences labs in Iran, Germany, Belgium (UMONS), Canada (USASK), Singapore (NUS) and Australia (SAHMRI), Saeed brings an impressive background into the ºÚÁÏÍø´óÊÂ¼Ç node helping to bring MPI as a novel tracer imaging method to the next level. He so far published more than 50 papers.
  • Book Chapters | 2018
    Lahooti A; Shanehsazzadeh S; Laurent S, 2018, 'Chapter 7 Dual-Modality Imaging', in Iron Oxide Nanoparticles for Biomedical Applications, Elsevier, pp. 165 - 196,
    Book Chapters | 2018
    Lahooti A; Shanehsazzadeh S; Laurent S, 2018, 'Dual-Modality Imaging', in Iron Oxide Nanoparticles for Biomedical Applications, Elsevier, pp. 165 - 196,
    Book Chapters | 2017
    Laurent S; Lahooti A; Shanehsazzadeh S; Muller RN, 2017, 'Nano delivery systems', in Drug Delivery Systems, pp. 277 - 342,
  • Journal articles | 2025
    Abdibastami A; Poerwoprajitno AR; Ramadhan ZR; Shanehsazzadeh S; Bongers A; Forest C; Gooding JJ; Tilley RD, 2025, 'How octopod Mn–Fe oxide nanoparticle tracers minimize relaxation time and enhance MPI resolution', Nanoscale, 17, pp. 21463 - 21467,
    Journal articles | 2025
    Duong HTK; Poerwoprajitno AR; Bongers A; Shanehsazzadeh S; Abdibastami A; Sulway S; Rich A; Gooding JJ; Tilley RD, 2025, 'Understanding the Influence of Gd Deposition on the MPI and MRI Performance of Fe3O4 Nanoparticles for Multimodal Imaging Applications', Journal of Physical Chemistry B, 129, pp. 1774 - 1783,
    Journal articles | 2025
    Rahardjo G; Shanehsazzadeh S; Niedermayer G; Liu GJ; Parmar A; Zahra D; Arthur A; Hamze H; Gamage R; Hwang MJ; Forbes M; Sen MK; Gyengesi E; Münch G, 2025, 'Molecular imaging of glial activation in the GFAP-IL6 chronic inflammation mouse model with TSPO radioligand 18F-PBR111', Discover Neuroscience, 20,
    Journal articles | 2025
    Shanehsazzadeh S; Bongers A, 2025, 'Evaluation of the Effects of Food and Fasting on Signal Intensities from the Gut Region in Mice During Magnetic Particle Imaging (MPI) †', Magnetochemistry, 11,
    Journal articles | 2024
    Abdibastami A; Gloag L; Prada JP; Duong HTK; Shanehsazzadeh S; Sulway SA; Cheong S; Hackbarth H; Bedford NM; Jameson GNL; Bongers A; Gooding JJ; Tilley RD, 2024, 'How Size and Composition of Cobalt Doped Iron Oxide Nanoparticle Tracers Enhance Magnetic Particle Imaging Performance', Chemistry of Materials, 36, pp. 8773 - 8781,
    Journal articles | 2024
    Li Z; Kovshova T; Malinovskaya J; Knoll J; Shanehsazzadeh S; Osipova N; Chernysheva A; Melnikov P; Gelperina S; Wacker MG, 2024, 'Blood-Nanoparticle Interactions Create a Brain Delivery Superhighway for Doxorubicin', International Journal of Nanomedicine, 19, pp. 2039 - 2056,
    Journal articles | 2024
    Zhang Q; Sun B; Shanehsazzadeh S; Bongers A; Gu Z, 2024, 'Engineering Zn/Fe Mixed Metal Oxides with Tunable Structural and Magnetic Properties for Magnetic Particle Imaging', Nanomaterials, 14,
    Journal articles | 2023
    Kim Duong HT; Abdibastami A; Gloag L; Bongers A; Shanehsazzadeh S; Nelson M; Cousins A; Bayat N; McCalmont H; Lock RB; Sulway S; Biazick J; Justin Gooding J; Tilley RD; Gooding J; Duong HTK, 2023, 'Small zinc doped iron oxide tracers for magnetic particle imaging', Journal of Magnetism and Magnetic Materials, 587,
    Journal articles | 2022
    Villa Nova M; Lin TP; Shanehsazzadeh S; Jain K; Ng SCY; Wacker R; Chichakly K; Wacker MG, 2022, 'Nanomedicine Ex Machina: Between Model-Informed Development and Artificial Intelligence', Frontiers in Digital Health, 4, pp. 799341,
    Journal articles | 2021
    Gao GF; Ashtikar M; Kojima R; Yoshida T; Kaihara M; Tajiri T; Shanehsazzadeh S; Modh H; Wacker MG, 2021, 'Predicting drug release and degradation kinetics of long-acting microsphere formulations of tacrolimus for subcutaneous injection', Journal of Controlled Release, 329, pp. 372 - 384,
    Journal articles | 2020
    Lahooti A; Shanehsazzadeh S; Laurent S, 2020, 'Preliminary studies of 68Ga-NODA-USPION-BBN as a dual-modality contrast agent for use in positron emission tomography/magnetic resonance imaging', Nanotechnology, 31,
    Journal articles | 2019
    Sakhtianchi R; Darvishi B; Mirzaie Z; Dorkoosh F; Shanehsazzadeh S; Dinarvand R, 2019, 'Pegylated magnetic mesoporous silica nanoparticles decorated with AS1411 Aptamer as a targeting delivery system for cytotoxic agents', Pharmaceutical Development and Technology, 24, pp. 1063 - 1075,
    Journal articles | 2017
    Farzadniya A; Faeghi F; Shanehsazzadeh S, 2017, 'Quantitative Effect of Magnetic Field Strength on PEGylated Superparamagnetic Iron Oxide Nanoparticles', Applied Magnetic Resonance, 48, pp. 597 - 607,
    Journal articles | 2017
    Lahooti A; Sarkar S; Saligheh Rad H; Gholami A; Nosrati S; Muller RN; Laurent S; Grüttner C; Geramifar P; Yousefnia H; Mazidi M; Shanehsazzadeh S, 2017, 'PEGylated superparamagnetic iron oxide nanoparticles labeled with 68Ga as a PET/MRI contrast agent: a biodistribution study', Journal of Radioanalytical and Nuclear Chemistry, 311, pp. 769 - 774,
    Journal articles | 2017
    Nikzad M; Jalilian AR; Shirvani-Arani S; Arabieh M; Shanesazzadeh S; Golchoobian H, 2017, 'Development and assessment of Sm-153-zoledronate complex as a possible bone pain palliative agent', IRANIAN JOURNAL OF NUCLEAR MEDICINE, 25, pp. 81 - 91,
    Journal articles | 2017
    Shanehsazzadeh S; Jalilian AR; Lahooti A; Geramifar P; Beiki D; Yousefnia H; Rabiee A; Mazidi M; Mirshojaei SF; Maus S, 2017, 'Preclinical evaluation of 68Ga-MAA from commercial available 99mTc-MAA Kit', Iranian Journal of Pharmaceutical Research, 16, pp. 1415 - 1423
    Journal articles | 2016
    Azhdarzadeh M; Atyabi F; Saei AA; Varnamkhasti BS; Omidi Y; Fateh M; Ghavami M; Shanehsazzadeh S; Dinarvand R, 2016, 'Theranostic MUC-1 aptamer targeted gold coated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging and photothermal therapy of colon cancer', Colloids and Surfaces B Biointerfaces, 143, pp. 224 - 232,
    Journal articles | 2016
    Fazaeli Y; Shanehsazzadeh S; Lahooti A; Feizi S; Jalilian A, 2016, 'Preclinical dosimetric estimation of [111In] 5, 10, 15, 20-tetra phenyl porphyrin complex as a possible imaging/PDT agent', Radiochimica Acta, 104, pp. 327 - 336,
    Journal articles | 2016
    Hajesmaeelzadeh F; Shanehsazzadeh S; Grüttner C; Daha FJ; Oghabian MA, 2016, 'Effect of coating thickness of iron oxide nanoparticles on their relaxivity in the MRI', Iranian Journal of Basic Medical Sciences, 19, pp. 166 - 171
    Journal articles | 2016
    Hatamie S; Ahadian MM; Ghiass MA; Iraji zad A; Saber R; Parseh B; Oghabian MA; Shanehsazzadeh Zadeh S, 2016, 'Graphene/cobalt nanocarrier for hyperthermia therapy and MRI diagnosis', Colloids and Surfaces B Biointerfaces, 146, pp. 271 - 279,
    Journal articles | 2016
    Lahooti A; Sarkar S; Laurent S; Shanehsazzadeh S, 2016, 'Dual nano-sized contrast agents in PET/MRI: a systematic review', Contrast Media and Molecular Imaging, 11, pp. 428 - 447,
    Journal articles | 2016
    Mirsadeghi S; Shanehsazzadeh S; Atyabi F; Dinarvand R, 2016, 'Effect of PEGylated superparamagnetic iron oxide nanoparticles (SPIONs) under magnetic field on amyloid beta fibrillation process', Materials Science and Engineering C, 59, pp. 390 - 397,
    Journal articles | 2016
    Nosrati S; Shanehsazzadeh S; Yousefnia H; Gholami A; Grüttner C; Jalilian AR; Hosseini RH; Lahooti A, 2016, 'Biodistribution evaluation of 166Ho–DTPA–SPION in normal rats', Journal of Radioanalytical and Nuclear Chemistry, 307, pp. 1559 - 1566,
    Journal articles | 2016
    Shanehsazzadeh S; Grüttner C; Yousefnia H; Lahooti A; Gholami A; Nosrati S; Zolghadri S; Anijdan SHM; Lotfabadi A; Varnamkhasti BS; Daha FJ; Jalilian AR, 2016, 'Development of 177Lu-DTPA-SPIO conjugates for potential use as a dual contrast SPECT/MRI imaging agent', Radiochimica Acta, 104, pp. 337 - 344,
    Journal articles | 2016
    Yousefnia H; Zolghadri S; Sadeghi HR; Naderi M; Jalilian AR; Shanehsazzadeh S, 2016, 'Preparation and biological assessment of 177Lu-BPAMD as a high potential agent for bone pain palliation therapy: comparison with 177Lu-EDTMP', Journal of Radioanalytical and Nuclear Chemistry, 307, pp. 1243 - 1251,
    Journal articles | 2015
    Fakhari A; Jalilian AR; Yousefnia H; Shanehsazzadeh S; Bahrami-Samani A; Johari-Daha F; Shafiee-Ardestani M; Khalaj A, 2015, 'Preparation, Biological Evaluation and Dosimetry Studies of Yb-175-Bis-Phosphonates for Palliative Treatment of Bone Pain', MOLECULAR IMAGING AND RADIONUCLIDE THERAPY, 24, pp. 110 - 119,
    Journal articles | 2015
    Najafian N; Shanehsazzadeh S; Hajesmaeelzadeh F; Lahooti A; Gruettner C; Oghabian MA, 2015, 'Effect of Functional Group and Surface Charge of PEG and Dextran-Coated USPIO as a Contrast Agent in MRI on Relaxivity Constant', Applied Magnetic Resonance, 46, pp. 685 - 692,
    Journal articles | 2015
    Sadeghzadeh M; Shanehsazzadeh S; Lahooti A, 2015, 'Assessment of the effective absorbed dose of 4-benzyl-1-(3-[125I]-iodobenzylsulfonyl)piperidine in humans on the basis of biodistribution data of rats', Nuclear Medicine Communications, 36, pp. 90 - 94,
    Journal articles | 2015
    Shanehsazzadeh S; Gruettner C; Lahooti A; Mahmoudi M; Allen BJ; Ghavami M; Daha FJ; Oghabian MA, 2015, 'Monoclonal antibody conjugated magnetic nanoparticles could target MUC-1-positive cells in vitro but not in vivo', Contrast Media and Molecular Imaging, 10, pp. 225 - 236,
    Journal articles | 2015
    Shanehsazzadeh S; Lahooti A; Hajipour MJ; Ghavami M; Azhdarzadeh M, 2015, 'External magnetic fields affect the biological impacts of superparamagnetic iron nanoparticles', Colloids and Surfaces B Biointerfaces, 136, pp. 1107 - 1112,
    Journal articles | 2015
    Shanehsazzadeh S; Lahooti A; Shirmardi SP; Erfani M, 2015, 'Comparison of estimated human effective dose of 67Ga- and 99mTc-labeled bombesin based on distribution data in mice', Journal of Radioanalytical and Nuclear Chemistry, 305, pp. 513 - 520,
    Journal articles | 2015
    Shanehsazzadeh S; Lahooti A; Yousefnia H; Geramifar P; Jalilian AR, 2015, 'Comparison of estimated human dose of 68Ga-MAA with 99mTc-MAA based on rat data', Annals of Nuclear Medicine, 29, pp. 745 - 753,
    Journal articles | 2015
    Shanehsazzadeh S; Yousefnia H; Jalilian AR; Zolghadri S; Lahooti A, 2015, 'Estimated human absorbed dose for 68Ga-ECC based on mice data: comparison with 67Ga-ECC', Annals of Nuclear Medicine, 29, pp. 475 - 481,
    Journal articles | 2015
    Shanehsazzadeh S; Yousefnia H; Lahooti A; Zolghadri S; Jalilian AR; Afarideh H, 2015, 'Assessment of human effective absorbed dose of 67 Ga–ECC based on biodistribution rat data', Annals of Nuclear Medicine, 29, pp. 118 - 124,
    Journal articles | 2015
    Yousefnia H; Zolghadri S; Shanehsazzadeh S, 2015, 'Estimated human absorbed dose of 177Lu-BPAMD based on mice data: Comparison with 177Lu-EDTMP', Applied Radiation and Isotopes, 104, pp. 128 - 135,
    Journal articles | 2014
    Omid H; Oghabian MA; Ahmadi R; Shahbazi N; Hosseini HRM; Shanehsazzadeh S; Zangeneh RN, 2014, 'Synthesizing and staining manganese oxide nanoparticles for cytotoxicity and cellular uptake investigation', Biochimica Et Biophysica Acta General Subjects, 1840, pp. 428 - 433,
    Journal articles | 2014
    Shanehsazzadeh S; Lahooti A, 2014, 'Biodistribution of 80 nm iron oxide nanoparticles labeled with Tc-99m in Balb/c mice', NUCLEAR MEDICINE AND BIOLOGY, 41, pp. 625 - 625,
    Journal articles | 2013
    Jahanbakhsh R; Atyabi F; Shanehsazzadeh S; Sobhani Z; Adeli M; Dinarvand R, 2013, 'Modified Gadonanotubes as a promising novel MRI contrasting agent', Daru Journal of Pharmaceutical Sciences, 21,
    Journal articles | 2013
    Lahooti A; Shanehsazzadeh S; Jalilian AR; Tavakoli MB, 2013, 'Assessment of effective absorbed dose of 111in-DTPA-buserelin in human on the basis of biodistribution rat data', Radiation Protection Dosimetry, 154, pp. 1 - 8,
    Journal articles | 2013
    Oghabian MA; Gharehaghaji N; Masoudi A; Shanehsazzadeh S; Ahmadi R; Majidi RF; Hosseini HRM, 2013, 'Effect of Coating Materials on Lymph Nodes Detection Using Magnetite Nanoparticles', Advanced Science, Engineering and Medicine, 5, pp. 37 - 45,
    Journal articles | 2013
    Shanehsazzadeh S; Oghabian MA; Allen BJ; Amanlou M; Masoudi A; Daha FJ, 2013, 'Evaluating the effect of ultrasmall superparamagnetic iron oxide nanoparticles for a long-term magnetic cell labeling', Journal of Medical Physics, 38, pp. 34 - 40,
    Journal articles | 2013
    Shanehsazzadeh S; Oghabian MA; Daha FJ; Amanlou M; Allen BJ, 2013, 'Biodistribution of ultra small superparamagnetic iron oxide nanoparticles in BALB mice', Journal of Radioanalytical and Nuclear Chemistry, 295, pp. 1517 - 1523,
    Journal articles | 2013
    Shanehsazzadeh S; Oghabian MA; Lahooti A; Abdollahi M; Abolghasem Haeri S; Amanlou M; Daha FJ; Allen BJ, 2013, 'Estimated background doses of [67Ga]-DTPA-USPIO in normal Balb/c mice as a potential therapeutic agent for liver and spleen cancers', Nuclear Medicine Communications, 34, pp. 915 - 925,
    Journal articles | 2011
    Amanlou M; Siadat SD; Ebrahimi SES; Alavi A; Aghasadeghi MR; Ardestani MS; Shanehsaz S; Ghorbani M; Mehravi B; Shafiee Alavidjeh M; Jabbari-Arabzadeh A; Abbasi M, 2011, 'Gd(3+)-DTPA-DG: novel nanosized dual anticancer and molecular imaging agent.', International Journal of Nanomedicine, 6, pp. 747 - 763
    Journal articles | 2011
    Shanehsazzadeh S; Lahooti A; Sadeghi HR; Jalilian AR, 2011, 'Estimation of human effective absorbed dose of 67Ga-cDTPA-gonadorelin based on biodistribution rat data', Nuclear Medicine Communications, 32, pp. 37 - 43,
    Journal articles | 2010
    Jalilian AR; Shanehsazzadeh S; Akhlaghi M; Kamali-Dehghan M; Moradkhani S, 2010, 'Development of [111In]-DTPA-buserelin for GnRH receptor studies', Radiochimica Acta, 98, pp. 113 - 119,
    Journal articles | 2010
    Moghaddam AK; Jalilian AR; Hayati V; Shanehsazzadeh S, 2010, 'Determination of human absorbed dose of 201Tl(III)-DTPA-HIgG based on biodistribution data in rats', Radiation Protection Dosimetry, 141, pp. 269 - 274,
    Journal articles | 2009
    Shanehsazzadeh S; Jalilian AR; Sadeghi HR; Allahverdi M, 2009, 'Determination of human absorbed dose of 67GA-DTPA-ACTH based on distribution data in rats', Radiation Protection Dosimetry, 134, pp. 79 - 86,
    Journal articles | 2008
    JALILIAN AR; SHANESAZZADEH S; ROWSHANFARZAD P; BOLOURINOVIN F; MAJDABADI A, 2008, 'Biodistribution study of [61Cu]pyruvaldehyde-bis (N-4-methylthiosemicarbazone) in normal rats as a PET tracer', Nuclear Science and Techniques Hewuli, 19, pp. 159 - 164,
    Journal articles | 2008
    Jalilian AR; Sardari D; Kia L; Rowshanfarzad P; Garousi J; Akhlaghi M; Shanehsazzadeh S; Mirzaii M, 2008, 'Preparation, quality control and biodistribution studies of two [ 111In]-rituximab immunoconjugates', Scientia Pharmaceutica, 76, pp. 151 - 170,
    Journal articles | 2008
    Jalilian AR; Shanehsazzadeh S; Akhlaghi M; Garoosi J; Rajabifar S; Tavakoli MB, 2008, 'Preparation and evaluation of [67Ga]-DTPA-β-1-24- corticotrophin in normal rats', Radiochimica Acta, 96, pp. 435 - 439,
    Journal articles | 2008
    Jalilian AR; Shanehsazzadeh S; Akhlaghi M; Garousi J; Rajabifar S; Tavakoli MB, 2008, 'Preparation and biodistribution of [67Ga]-DTPA-gonadorelin in normal rats', Journal of Radioanalytical and Nuclear Chemistry, 278, pp. 123 - 129,
    Journal articles | 2008
    Salamat MR; Rostampour N; Shanehsazzadeh S; Tavakoli MB; Siavash M; Almasi T, 2008, 'Assessment of bone mineral density with dual energy X-ray absorptiometry in pre- and post-menopausal women', Iranian Journal of Radiation Research, 6, pp. 107 - 111
    Journal articles | 2007
    Shanehsaz Zadeh S; Salehi A; Mehri A, 2007, 'Comparison of different invasive types of refractive errors operation', Journal of Isfahan Medical School, 24
  • Other | 2021
    Shanehsazzadeh S; lahooti A; Babyn PS, 2021, "Prognostic value of radiomics parameters of PET/CT in patients with oropharyngeal carcinoma: A systematic review and meta- analysis", ,
    Other | 2021
    Shanehsazzadeh S; lahooti A, 2021, "Prognostic value of radiomics parameters of PET/CT in patients with oropharyngeal carcinoma: A systematic review and meta- analysis", ,
    Conference Papers | 2013
    Lahooti A; Shanehsazzadeh S; Oghabian MA; Allen BJ, 2013, 'Assessment of human effective absorbed dose of Tc-99m-USPIO based on biodistribution rat data', in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, WILEY-BLACKWELL, pp. S258 - S258,
    Conference Papers | 2013
    Shanehsazzadeh S; Oghabian MA; Allen BJ; Amanlou M; Johari Daha F, 2013, 'Evaluating the effect of USPIO nanoparticles for 21 days post magnetic cell labeling', in Ifmbe Proceedings, pp. 2204 - 2207,
    Conference Papers | 2013
    Shanehsazzadeh S; Oghabian MA; Lahooti A; Allen BJ, 2013, 'Development of ultra small super paramagnetic iron oxide nanoparticles labeled with Gallium 67 as a dual modality probe', in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, WILEY-BLACKWELL, pp. S236 - S236,
    Conference Papers | 2011
    Moghaddam AK; Jalilian AR; Hayati V; Shanehsazzadeh S; Dodangeh A, 2011, 'Evaluation And Calculation of Human absorbed dose of (201) Tl(III)-DTPA-HIgG based on biodistribution data in rats', in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, WILEY-BLACKWELL, pp. S347 - S347,
    Conference Papers | 2009
    Shanehsazzadeh S; Jalilian A, 2009, 'DEVELOPMENT OF [67GA]-DTPA-GONADORELIN IN NORMAL RATS', in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, JOHN WILEY & SONS LTD, pp. S326 - S326,