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Dr Sandra Fok

Dr Sandra Fok

Research Associate
Research & Enterprise
Bio-medical Imaging Facility

Sandra is a research associate in the Biomedical Imaging Facility within the Mark Wainwright Analytical Centre.  Her research interest are in cancer cell migration/invasion and neuroscience.  She specializes in advanced light and optical imaging, including but not limited to 

- Confocal microscopy including FRET and FRAP

- Multi-photon imaging

- Selective plan illumination microscopy (Lightsheet)  - Gaussian and Lattice

- Live cell imaging

- Intravital imaging (mouse, rat and zebrafish)

- Slide scanning

- Ground state depletion microscopy

- Laser microdissection microscopy

- Tranmission and scanning electron microscopy (Biological)

Mobile
+61405 608 635
Location
Desk 2.11, Rm 2061, Level 2, BioScience South (E26), University of New South Wales
  • Book Chapters | 2011
    2011, 'Matrix Scaffolds in Cancer Cell Biology; Physiological Representation and Nanoscale Characterisation', in Nanomedicine and Cancer, CRC Press, pp. 150 - 167,
    Book Chapters | 2011
    2011, 'Matrix scaffolds in cancer cell biology; Physiological representation and nanoscale characterisation', in Nanomedicine and Cancer, pp. 142 - 159
    Book Chapters | 2011
    2011, 'The continuum of epithelial mesenchymal transition - implication of hybrid states for migration and survival in development and cancer.', in Cancer Metastasis Biologic Basis and Therapeutics, Cambridge University Press
  • Journal articles | 2022
    2022, 'Use of High-Refractive Index Hydrogels and Tissue Clearing for Large Biological Sample Imaging', Gels, 8, pp. 32 - 32,
    Journal articles | 2021
    2021, 'Ground state depletion microscopy as a tool for studying microglia–synapse interactions', Journal of Neuroscience Research, 99, pp. 1515 - 1532,
    Journal articles | 2019
    2019, 'Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice', Frontiers in Molecular Neuroscience, 12,
    Journal articles | 2019
    2019, 'Neuregulin 1 Deficiency Modulates Adolescent Stress-Induced Dendritic Spine Loss in a Brain Region-Specific Manner and Increases Complement 4 Expression in the Hippocampus', Schizophrenia Bulletin, 45, pp. 339 - 349,
    Journal articles | 2019
    2019, 'Translocator protein localises to CD11b + macrophages in atherosclerosis', Atherosclerosis, 284, pp. 153 - 159,
    Journal articles | 2018
    Hart G; Bradfield LA; Fok SY; Chieng B; Balleine BW, 2018, 'The Bilateral Prefronto-striatal Pathway Is Necessary for Learning New Goal-Directed Actions', Current Biology, 28, pp. 2218 - 2229.e7,
    Journal articles | 2018
    Kassem MS; Fok SY Y; Smith KL; Kuligowski M; Balleine BW, 2018, 'A novel, modernized Golgi-Cox stain optimized for CLARITY cleared tissue', Journal of Neuroscience Methods, 294, pp. 102 - 110,
    Journal articles | 2018
    Stefen H; Hassanzadeh-Barforoushi A; Brettle M; Fok S; Suchowerska AK; Tedla N; Barber T; Warkiani ME; Fath T, 2018, 'A Novel Microfluidic Device-Based Neurite Outgrowth Inhibition Assay Reveals the Neurite Outgrowth-Promoting Activity of Tropomyosin Tpm3.1 in Hippocampal Neurons', Cellular and Molecular Neurobiology, 38, pp. 1557 - 1563,
    Journal articles | 2018
    2018, 'Light-sheet microscopy as a tool to understanding the behaviour of Polyion complex micelles for drug delivery', Chemical Communications, 54, pp. 12618 - 12621,
    Journal articles | 2017
    Patel S; Fok SY Y; Stefen H; Tomanić T; Parić E; Herold R; Brettle M; Djordjevic A; Fath T, 2017, 'Functional characterisation of filamentous actin probe expression in neuronal cells', PLoS ONE, 12,
    Journal articles | 2017
    Suchowerska AK; Fok S; Stefen H; Gunning PW; Hardeman EC; Power J; Fath T, 2017, 'Developmental profiling of tropomyosin expression in mouse brain reveals Tpm4.2 as the major post-synaptic tropomyosin in the mature brain', Frontiers in Cellular Neuroscience, 11,
    Journal articles | 2014
    Banati RB; Middleton RJ; Chan R; Hatty CR; Wai-Ying Kam W; Quin C; Graeber MB; Parmar A; Zahra D; Callaghan P; Fok S; Howell NR; Gregoire M; Szabo A; Pham T; Davis E; Liu GJ, 2014, 'Positron emission tomography and functional characterization of a complete PBR/TSPO knockout', Nature Communications, 5,
    Journal articles | 2014
    Chohan TW; Boucher AA; Spencer JR; Kassem MS; Hamdi AA; Karl T; Fok SY; Bennett MR; Arnold JC, 2014, 'Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice', Schizophrenia Bulletin, 40, pp. 1272 - 1284,
    Journal articles | 2014
    Rahman T; Davies DS; Tannenberg RK; Fok S; Shepherd C; Dodd PR; Cullen KM; Goldsbury C, 2014, 'Cofilin rods and aggregates concur with tau pathology and the development of alzheimer's disease', Journal of Alzheimer's Disease, 42, pp. 1443 - 1460,
    Journal articles | 2014
    Sajjan S; Holsinger RM D; Fok S; Ebrahimkhani S; Rollo JL; Banati RB; Graeber MB, 2014, 'Up-regulation of matrix metallopeptidase 12 in motor neurons undergoing synaptic stripping', Neuroscience, 274, pp. 331 - 340,
    Journal articles | 2012
    Raviraj V; Fok S; Zhao J; Chien HY; Lyons JG; Thompson EW; Soon L, 2012, 'Regulation of ROCK1 via Notch1 during breast cancer cell migration into dense matrices', BMC Cell Biology, 13,
    Journal articles | 2011
    Fok S; Whiting J, 2011, 'Microscopy and microanalysis techniques for R&D in the mining industry', AusIMM Bulletin, pp. 26 - 31
    Journal articles | 2008
    Lyons JG; Patel V; Roue NC; Fok SY; Soon LL; Halliday GM; Gutkind JS, 2008, 'Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytes', Cancer Research, 68, pp. 4525 - 4530,
    Journal articles | 2008
    2008, 'Planar microfluidic chamber for generation of stable and steep chemoattractant gradients', Biophysical Journal, 95, pp. 1523 - 1530,
    Journal articles | 2007
    Tchou-Wong KM; Fok SY Y; Rubin JS; Pixley F; Condeelis J; Braet F; Rom W; Soon LL, 2007, 'Erratum: Rapid chemokinetic movement and the invasive potential of lung cancer cells; a functional molecular study', BMC Cancer, 7,
    Journal articles | 2006
    Fok SY Y; Rubin JS; Pixley F; Condeelis J; Braet F; Soon LL, 2006, 'Rapid chemokinetic movement and the invasive potential of lung cancer cells; a functional molecular study', BMC Cancer, 6,
  • Preprints | 2021
    2021, Use of high-refractive index hydrogels and tissue clearing for large biological sample imaging (Preprint), ,
    Preprints | 2020
    2020, Use of high-refractive index hydrogels and tissue clearing for large biological sample imaging, ,
    Preprints | 2018
    2018, Translocator Protein Localises To CD11b+ Macrophages In Atherosclerosis, ,