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Memory and Ageing Study 2 (MAS2)

One of Australia鈥檚 largest studies of ageing and cognitive health.

Description

The Sydney Memory and Ageing Study (MAS), is one of Australia鈥檚 largest and longest running studies of ageing and cognitive health. MAS began in 2005 with the aims of investigating 听rates and predictors of healthy cognitive ageing, mild cognitive impairment (MCI) and dementia in older Australians. Over the last 14 years, MAS has collected biomarker, genetic/epigenomic, neuroimaging, cognitive, proteomics/lipidomics, health, and lifestyle data to determine what factors are associated with cognitively normal ageing and progression to MCI or dementia.

Aims

  • Chart the generational change in the physical, psychological, social, and cognitive/ brain health in Australians aged 70-90 years old.
  • Examine the effects of living through the pandemic on mental health in older people.
  • Determine changes in risk factors for cardio- and cerebrovascular disease and cognitive decline and their relative contributions to cognitive decline.
  • Determine changes in use of health services and pathways to care and factors associated with health care.
Project type

Longitudinal Studies

Research project

Memory and Ageing Study 2

Project status

Current

Recruitment

Recruitment

Individuals aged 70-90 will be recruited over 15 months from 2023-2025. Eligibility will be confirmed by telephone. Informed consent will be obtained from participants and informants.

Prior to the first visit, participants would be asked to complete various online questionnaires assessing physical, psychological, social, and cognitive/ brain health. Participants then complete face-to-face assessments comprising a neuropsychological and medical examination, ideally at 黑料网大事记 Sydney.

Each participant鈥檚 informant will complete a phone interview and additional questionnaires as part of the study partner component of MAS2.

Individuals aged 70-90 will be recruited over 15 months from 2023-2025. Eligibility will be confirmed by telephone. Informed consent will be obtained from participants and informants.

Prior to the first visit, participants would be asked to complete various online questionnaires assessing physical, psychological, social, and cognitive/ brain health. Participants then complete face-to-face assessments comprising a neuropsychological and medical examination, ideally at 黑料网大事记 Sydney.

Each participant鈥檚 informant will complete a phone interview and additional questionnaires as part of the study partner component of MAS2.

Add-on studies

Following the face-to-face assessment, participants will be invited to participate in one or more add-on studies with the following aims:

  • Vision and Eye:听Determine ocular biomarkers for cardio- and cerebrovascular disease, cognitive decline and dementia.
  • Falls and Balance:听Determine the best prognostic test/s for falls in a large representative sample of community living older people and determine how novel assessment measures of gait adaptability, sleep quantity and remotely collected gait and physical activity measures predict falls.
  • Bone Density and Physical Activity:听Explore the associations between bone density, physical activity and cognitive ageing.
  • Cardiometabolic Mind Your Heart:听Explore the relationship between cardiometabolic biomarkers and brain ageing and cerebral vascular change.

Staff

    • Professor Henry Brodaty
    • Professor Perminder Sachdev
    • Professor Colin Masters
    • Professor Maria Fiatarone Singh
    • Professor Annette Dobson
    • Professor Aletta E Schutte
    • Professor Henry Cutler
    • Professor Carol Brayne
    • Dr Nicole Kochan
    • Dr Katya Numbers
    • Dr Karen Mather
    • Assoc Professor Wei Wen
    • Professor Katherine Samaras
    • Ms Heidi Welberry
    • Dr Chun Pan Lam
    • Ms Fleur de Crespigny
    • Michael Schapiro
    • Ms Tiffany Chau
    • Dr Amanda Selwood
    • Ms Deena Sharabas
    • Mr Matthew Barwell
    • Ms Abbie Lucian
    • Ms Georgina Brown
    • Dr Suraj Samtani
    • Mr Ping-Hsiu Lin
    • Ms Saly Mahalingam
    • Ms Zara Page

Add-on studies
    • Prof Lisa Keay
    • Dr Angelica Ly
    • Dr Jessie Huang-Lung
    • Ms Annita Duong
    • Professor Stephen Lord
    • Professor Kim Delbaere
    • Dr Jasmine Menant
    • Mr Cameron Hicks
    • Professor Jacqueline Center
    • Professor Maria Fiatarone Singh
    • Professor Katherine Samaras
    • Professor Jason Kovacic
    • Professor Alta Schutte
    • Dr Louise Goodall

Contact

To join MAS2, please visit:听

E:听mas2@unsw.edu.au

W:听