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Research projects

The Centre for Healthy Brain Ageing (CHeBA) conducts extensive research projects on cognitive health and ageing.
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Sydney Memory & Ageing Study (MAS)

The Sydney Memory and Ageing Study (MAS), is one of Australia’s largest and longest running studies of ageing and cognitive health. In 2005, MAS recruited 1037 older adults without dementia, aged 70–90, and assessed them every two years for the next 14 years.

Longitudal study
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Memory & Ageing Study 2 (MAS2)

Following on from the original Sydney Memory and Ageing Study (MAS), which is one of Australia’s largest and longest running studies of ageing and cognitive health, MAS2 looks at generational changes in rates and predictors of health and cognitive decline in older adult.

Longitudal study
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Sydney Centenarian Study

A longitudinal study that explores the genetic and environmental determinants of extreme longevity by examining the cognition, health, care needs, brain structure and genetics of Australia’s oldest old.

Longitudinal study
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CHeBA news on 'Researching Twins to Better Understand Memory Decline and other cognitive abilities.

Older Australian Twins Study (OATS)

The Older Australian Twins Study is a longitudinal study investigating healthy brain ageing in older twins (65+ years). Healthy ageing is characterised by low levels of disability, high cognitive and functional capacity, and an active engagement in life. 

Longitudinal Study
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Assessment chart for the Older Australian Twins Study (OATS) showing data across multiple waves from 2006 to 2017. Includes participant numbers, percentages for blood samples, MRIs, and PET scans, and categories for lost to follow-up such as withdrawn, deceased, and siblings. Notes indicate 'NA' for not assessed.

Maintain Your Brain

Maintain Your Brain is a randomised controlled trial of multiple online interventions designed to target modifiable risk factors for dementia in general and AD in particular.

Longitudinal Study
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Dementias Platform Australia (DPAU)

The objective of DPAU is to support researcher access to data from one or several Contributing Research Studies (CRS) and thereby enable new insights into ageing, ageing-related diseases and dementia risk, with the aim of transforming the epidemiology of ageing and dementia.

All CHeBA projects
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Dementia Prevalence

This project aims to define global dementia prevalence in centenarians and near-centenarians (95+) using uniform diagnostic criteria and explore universal risk and protective factors for dementia across 17 Population-Based Centenarian Studies from 11 countries.

All CHeBA projects
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CogSCAN

This study of Computer-Administered Neuropsychological tests in seniors is the first independent, systematic evaluation of four prominent and widely used computerised cognitive assessment instruments in healthy older adults and in people with mild cognitive impairment and dementia.

All CHeBA projects
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Neuropsychological Normative Study

Provides much needed Australian normative data for commonly used neuropsychological tests and cognitive screening instruments in older persons including the oldest-old, near-Centenarians and Centenarians.

All CHeBA projects
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