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Lipid Nanoparticle Production, Purification and Quality Control

Scientists at work at the RNA Accelerator – the core facility within the ºÚÁÏÍø´óÊÂ¼Ç RNA Institute designed to expedite the discovery, manufacture and translation of RNA-based therapeutics and other products.

This course provides comprehensive theory and hands-on training in the lipid nanoparticle (LNP) formulation of RNA therapeutics from handling starting materials through to finished RNA-LNPs.

The course covers multiple techniques relevant from the research bench up to large-scale manufacturing, as well as basic quality control to quantify and analyse product quality, including particle size and encapsulation efficiency. The course includes an overview of Quality Management Systems (QMS) requirements, Quality by Design principles, Bioprocess Engineering and Process Development-Validation, and insights into process tech transfer to GMP production facilities.

Course Details

¶Ù²¹³Ù±ð:ÌýMarch 16-20, 2026
Length: 5 days
Location: ºÚÁÏÍø´óÊÂ¼Ç Kensington campus
Fees: $5,000 per participant

Course Objectives

Give participants a combination of theory and practical, hands-on experience in producing, purifying and analysing the quality of RNA-LNPs for use in RNA therapeutics.

Learning Outcomes

Upon successful completion of the course, participants will:

  • Have a fundamental understanding of synthetic RNA, mRNA and RNA-LNP therapeutics manufacturing processes.
  • Have a sound understanding of RNA-LNP manufacturing processes.
  • Have a sound understanding of RNA-LNP purification processes.
  • Have a sound understanding of RNA-LNP quality control methods.
  • Gain hands-on experience in aseptic and RNA-LNP handling techniques.
  • Gain hands-on experience in production of RNA-LNPs.
  • Gain hands-on experience in purification of RNA-LNPs.
  • Gain hands-on experience in quality control of RNA-LNPs.
  • Have a fundamental understanding of Quality Management Systems (ISO 9001, GMP).
  • Have fundamental understanding of Quality by Design principles (ICH Q8) 
  • Have a fundamental understanding of Bioprocess Engineering, Drug, and Process Development Concepts 
  • Have a fundamental understanding of tech transfer from bench research to large-scale GMP manufacturing facilities.

Participants will have the option to receive a Certificate of Attendance (not assessed) or a Certificate of Completion (assessed).
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