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mRNA Enzymatic Production, Purification and Quality Control

An illustration of the molecular structures of siRNA and vaccine mRNA highlighting size differences between the two

This course provides comprehensive theory and hands-on training from design of RNA and DNA template constructs and production techniques from linearised DNA template starting material through to purified mRNA.

The course covers multiple techniques relevant from the research bench up to large-scale bioprocessing as well as basic quality control to quantify and analyse product quality. The course includes an overview of Quality Management Systems (QMS) requirements, Bioprocess Engineering and Process Development, and insights into process tech transfer to GMP production facilities.

Course Details

¶Ù²¹³Ù±ð:ÌýMarch 9-13, 2026
Length: 5 days
Location: ºÚÁÏÍø´óÊÂ¼Ç Kensington campus
Fees: $5,000 per participant

Course Objectives

Give participants a combination of theory and practical, hands-on experience in designing, producing, purifying and analysing the quality of mRNA for use in mRNA therapeutics.

Learning Outcomes

Upon successful completion of the course, participants will:

  • Have a fundamental understanding of mRNA-LNP therapeutics manufacturing processes.
  • Have a sound understanding of mRNA manufacturing processes.
  • Have a sound understanding of mRNA purification processes.
  • Have a sound understanding of mRNA quality control methods.
  • Gain hands-on experience in aseptic and mRNA handling techniques.
  • Gain hands-on experience in production of mRNA.
  • Gain hands-on experience in purification of mRNA.
  • Gain hands-on experience in quality control of mRNA.
  • Have a fundamental understanding of Quality Management Systems (ISO 9001, GMP).
  • Have a fundamental understanding of Bioprocess Engineering and Process Development concepts.
  • Have a fundamental understanding of tech transfer from bench research to large-scale GMP manufacturing facilities.

Participants will have the option to receive a Certificate of Attendance (not assessed) or a Certificate of Completion (assessed).
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